MS36-P08 Copper based Bio-MOFs: Challenges and possibilities in crystal engineering. Marius Kremer (Institute of Inorganic Chemistry, RWTH Aachen University, Aachen, Germany) Ulli Englert (Institute of Inorganic Chemistry, RWTH Aachen University, Aachen, Germany)email: Marius.Kremer@rwth-aachen.deMetal-organic frameworks present one of the fastest growing categories of structures published in the CCD. Due to their extreme structural and chemical diversity, MOFs can be deployed in many fields of modern chemistry like gas separation, hydrogen storage or catalysis [1]. Synthesising biologically non-hazardous and medically harmless MOFs provides interesting possibilities for different medical applications like site-targeted drug delivery or medical imaging [2] and might be used to replace toxic or hazardous compounds in many other fields. This shift towards a “greener” chemistry is not only potentially beneficial for working conditions and the environmental impact of the industry, but might also lead to an economical benefit, since most reactants used are easy to store, widely available and sometimes even easily recyclable. [3]
In our experiments, we synthesised coordination complexes from non-toxic copper salts and aspartic acid. Aspartic acid, featuring two carboxylato sites, might enable bridging between multiple copper cations, leading to extended framework structures. Different copper salts were used to synthesise coordination compounds in H2O and EtOH, the products were then analysed using X-Ray diffraction, IR-spectroscopy and CHN elemental analysis. Since growing single crystals suitable for X-Ray diffraction proved challenging, several different crystallization techniques were employed during the synthesis of the substances.

[1] Long, J. R. & Yaghi, O. M. (2009). Chem. Soc. Rev., 38, 1213-1214

[2] McKinlay, A., Morris, R., Horcajada, P., Férey, G., Gref, R., Couvreur, P & Serre, C. (2010). Angewandte Chemie International Edition, 49, 6260-6266

[3] Julien, P. A., Mottillo, C. & Friščić, T. (2017). Green Chem., 19, 2729-2747

Keywords: Bio-MOF, crystal engineering, coordination complex